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A review on the research progress of traditional Chinese medicine with anti-cancer effect targeting ferroptosis

This effect of Rac1 was initially demonstrated in Drosophila (Shuai et al., 2010) where controlled expression of dominant negative and constitutively active Rac1 mutants in the MBs using the Gal/UAS binary system delayed and facilitated aversive olfactory memory decay, respectively, without affecting memory acquisition (Shuai et al., 2010)

Together, our findings reinforce the longer-term safety profile and tolerability of this class of therapy and encourage further development in patients with end-stage liver disease

10.1126/science.286.5448.2358 [DOI] [PubMed] [Google Scholar] Rosen E