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Although less studies, the microbes can also have indirect effects though modulations of host the immune and other physiological effects (Zhang et al., 2012

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In addition, artemisinin increases ROS levels, and FIN56 binds and activates squalene synthase to accumulate ROS (Kang et al., 2019), leading to the depletion of endogenous antioxidant CoQ10 and then inducing ferroptosis by lipid peroxidation

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Ohmachi, M., et al

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1hk), resulting in a 7-fold higher so-called HERA score for REW than the WT antibody (Fig

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