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For example, grape seed extract, applied to normal human melanocyte and dermal fibroblast cells, was shown to enhance skin youthfulness by stimulating collagen and elastin production (133)

doi: 10.3389/fmed.2023.1124275 Received 14 December 2022 Accepted 27 February 2023 Published 22 March 2023 Volume 10 - 2023 Edited by Ana Sandoval-Rodriguez, University of Guadalajara, Mexico Reviewed by Angelo Armandi, University of Turin, Italy