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This is a sign of long-standing nerve compression and is a strong indication for surgical evaluation

Excess visceral fat (the fat stored around your organs): Drives insulin resistance Increases inflammatory cytokines Raises cardiovascular risk Increases dementia risk Disrupts hormone signaling Suppresses growth hormone Having more visceral fat is particularly concerning, as it surrounds internal organs and is strongly linked to higher risks of chronic diseases compared to subcutaneous fat

Patients receiving tirzepatide and sermorelin together require enhanced monitoring protocols beyond standard care for either medication alone, given the absence of established safety data for this combination

This distinction makes CJC 1295/Ipamorelin a safer, more physiological approach to GH optimization