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As with other antimuscarinic agents, the major action of atropine is a competitive or surmountable antagonism which can be overcome by increasing the concentration of acetylcholine at receptor sites of the effector organ (e.g., by using anticholinesterase agents which inhibit the enzymatic destruction of acetylcholine)

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Metagene plot (mean) of IgG control signal at the LSD1-bound regions within the 498 downregulated genes (top right) and 498 unaffected control genes (bottom right), for both for both parental (black) and edited K562 cells (pink) are shown

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