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R is an aromatic or an alkyl residue U.S

In contrast, the sibling (who also carries the L68Q mutation and was not on NAC between biopsies #1 and #2) showed significant progression in immunoreactivity, reflective of an increase in hCC protein complex deposition in the skin

Free Radic Biol Med 224:797808

This finding was contradicted by another study that showed that PsA patients with psoriatic skin manifestation had higher serum uric acid than PsA patients without PsO [53]