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MRPL21 promotes HCC proliferation through TP53 mutation-induced apoptotic resistance

31 Because serine is required (1) for the conversion of folic acid to its active form, (2) as a shuttle for methyl groups between the cytosol and the mitochondria, and (3) as a cofactor in the transsulfuration pathway of methionine/homocysteine metabolism, supplementation with betaine should be included with folic acid, cobalamin, and P5P to optimize the interrelated pathways of homocysteine metabolism

Our comprehensive transcriptomic analysis revealed twice as many differentially expressed genes (DEGs) in S

doi:10.1093/jhmas/IX.4.455