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Whereas non-cystic fibrosis cells upregulate CHAC1 following infection with various pathogens (including Pseudomonas aeruginosa , human coronavirus, cytomegalovirus, tick-borne flaviviruses, Zika virus, and Mycoplasma hominis ), cystic fibrosis cells show an impaired response

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However, thyroid cells do need to maintain a small quantity of ROS to incorporate into the thyroid enzymes they produce

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IB and IP products and WCL derived from HEK293 cells transfected with indicated constructs

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Huang et al., 2023)

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