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Substituted alkyl refers to an alkyl group having from 1 to 5, preferably 1 to 3, or more preferably 1 to 2 substituents selected from the group consisting of alkoxy, substituted alkoxy, acyl, acylamino, aminocarbonylamino, acyloxy, amino, substituted amino, the substituted alkyl groups include halogenated alkyl groups and particularly halogenated methyl groups such as trifluoromethyl, difluromethyl, fluoromethyl and the like

2023;83:1693709.e9 Narendra DP, Youle RJ

Adults exposed to excessive fluoride over a lifetime may have increased likelihood of bone fractures, and may also experience pain and tenderness

Considine, M