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10.Meloni T., Cagnazzo G., Dore A

Harnessing the innate and adaptive immune system for tissue repair and regeneration: considering more than macrophages

It is well known that oxidative stress is involved in the development of many chronic diseases such as cancer ( Reference Reuter, Gupta and Chaturvedi 1 ) , CVD ( Reference Heitzer, Schlinzig and Krohn 2 ) and diabetes ( Reference Ceriello and Motz 3 )

The consequent chronic inflammatory state is then localized where the trigger, either infection or injury, was present leading to persistent infections and medical disorders related to the affected organs or systemic immunoinflammatory and O&NS responses [3, 179]