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The diluent is directed slowly against the inside wall of the vial rather than sprayed onto the powder, and the vial is gently swirled rather than shaken, because vigorous agitation can shear peptide bonds and denature the material

However, in vitro experiments have shown that there is a 1000-fold discrepancy between the reaction with free Hb or intact RBCs (111)

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132 , 133 , 135 Thus, for BPC 157 application as a cytoprotective agent, we could likely envisage an analogy with the counteraction of the stomach lesion induced by NSAIDs much like the counteraction of all others adverse of NSAIDs effects, including the central disturbances