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Moreover, given the increased Th2 response and impaired Th1 antiviral response, the use of hydrocortisone could further potentiate this immunodeficiency and EBV reactivation [393, 394]

In these processes, berberine has been shown to reduce the expression of lipogenic enzymes, including fatty acid synthase and acetyl-CoA carboxylase, which are essential for lipid accumulation