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BDNF, brain-derived neurotrophic factor, is the central signaling molecule in neuronal survival, synaptic plasticity, and neurogenesis

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In a convenience sample of deceased NFL football players who donated their brains for research, 110 of 111 had neuropathological evidence of CTE, suggesting that CTE may be related to playing football [note that participation in the brain-donation program was likely motivated by players and their families awareness of links between head trauma and CTE

Serum tryptophan decrease correlates with immune activation and impaired quality of life in colorectal cancer