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doi:10.1080/01480545.2018.1485687

In contrast to common case reports from Africa, this condition is uncommon in the United States where most cases are secondary to the prolonged use of over-the-counter, low-concentration, cosmetic formulations of 2% hydroquinone

Virus was harvested 48 h and 72 h post transfection, filtered (0.45 m) and supplemented with polybrene (4 g/ml, Merck, Germany)

This indicated enhanced ferroptosis in fibroblast-like synoviocytes (FLSs) by downregulating PI3K-AKT-ERK1/2 signaling pathway and the activation of the P53 pathway which collectively contributed to reduced cell proliferation, migration, and invasion of FLSs