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437,438 Elevated serum levels of soluble intracellular adhesion molecule 1 (sICAM-1), indicative of increased vascular inflammation and/or endothelial dysfunction, have also been reported in PDPN

High fructose, free PA, HFD, hypoxia, ageing or disease can cause mitochondrial damage in vivo or in vitro in mammals (Reference Brand and Nicholls69Reference Marcovina, Sirtori and Peracino71)

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[53] Lucas J, Hsieh TC, Halicka HD, Darzynkiewicz Z, Wu JM