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The T cell dysfunction in ME/CFS trial (NCT06731179) utilizes T cell assays to assess immune dysfunction, focusing on T cell subfractions and their pathogenic role

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Neuroscience 148:535540

Specifically, expression of the gene ICOS was significantly negatively correlated with E2F6 expression, whereas U87 cell growth was reduced upon E2F6 knockout through short hairpin RNA (shRNA) [139]