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10.1016/j.drudis.2020.09.036 177 ZhaiY.ZhouZ.WangW.WangX.WangZ.DaiG.et al (2024)

Cellular studies have shown that exogenous NAD + can impact mitochondrial activity, such as boosting Krebs cycle and the ETC, but also impair genomic DNA replication and induce DNA replication stress due to impairment of pyrimidine biosynthesis 118

Each way affects how fast the B12 is absorbed and how often shots are needed

The antioxidant mechanism mediated by SOD is activated prior to RT SOD is one of the primary enzymatic defense mechanisms against ROS and is regarded as a key antioxidant marker