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Moreover, the hyperhomocysteinemia associated with an increased cardiovascular risk is stronger in non-insulin-dependent diabetes mellitus than in normal subjects (Hoogeveen et al, 1998)

While hotspot mutants account for nearly 30% of all p53-mutations, 70% of mutants remain unexplored [14]

commune , respectively (Jiamworanunkul 2019)

Based on these conflicted results, the association was speculated to be related to the clinical features of the population, stages of the disease, severity of copper excess, and types of detected specimens in these studies (Table 1)