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Pyroptosis activation is highly dependent on direct stimulation of immune cells by pathogen-associated molecular patterns, and its core pathological effect is the massive release of potent pro-inflammatory cytokines such as IL-1 and IL-18

Importance of chemokine (CC-motif) ligand 2 in breast cancer

Mechanical stressors dramatically alter the gene expression, morphology and function of retinal astrocytes and push the cells into a reactive state called astrogliosis that manifests as the inflammation and fibrosis of the lamina, and correlates with weakened ONH architecture, compromised blood supply and axonal loss (86, 98, 99)

4 Discussion 4.1 Summary of evidence This systematic review and meta-analysis indicate that the active components of Schisandra chinensis exhibit significant protective effects against liver injury in animal models