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Mechanism-based treatment for chemotherapy-induced peripheral neuropathic pain

The traditional heme production method extracts hemoglobin from the blood of pigs or other animals and then prepares free heme through enzymatic hydrolysis

Actin depolymerization of phagosomes was also ASMase-dependent in the BMMs because imipramine treatment of WT BMMs increased the ratio of cells possessing actin-coated phagosomes ( Figure 7D ), indicating that not only cell lines but also primary Ms use the SM-ceramide-axis to control phagosomal actin