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Telomerase, an enzyme produced naturally in the body, helps to decrease the progressive shortening of telomeres which may lead to age-related diseases

10.1083/jcb.200809046 J

10.1038/nature19058 Nature 149 TashiroA.YusteR

In contrast, in models with weight-dependent heterosynaptic plasticity, learning does not lead to runaway potentiation or depression of individual synapses