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Description

iScience 27 , 110657 (2024)

Neurodegeneration in HD follows a relatively stereotyped progression, beginning in the striatum and extending to other cortical and subcortical structures

185 mTORC1 signaling promotes the Warburg effect by upregulating and activating key glycolytic enzymes, including PKM2, HK2, and lactate dehydrogenase A (LDHA)