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The meningococcal genome has a glutamine synthetase but lacks a functional glutamate synthase and, therefore, a Glutamine Synthetase (GS)/Glutamine Oxoglutarate Aminotransferase (GOGAT) cycle, suggesting a major role for NADP-GDH in ammonia assimilation

This process can alter arginine and lysine residues in lens proteins, causing proteins to clump together and encouraging the formation of advanced glycation end products

Strategies targeting DNA methylation to treat RA have shown that regulatory T cells (Tregs) play a role in maintaining immune tolerance in the body, but the number of Tregs is significantly decrease in patients with RA

Physical dependence is a state that develops as a result of physiological adaptation in response to repeated drug use, manifested by withdrawal signs and symptoms after abrupt discontinuation or a significant dose reduction of a drug