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Breast cancer development and progression: risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis

The malonyl-CoA product is further converted by FASN to long-chain fatty acids

2013 Apr 3;309(13):135967

Through the production of antioxidant target genes, Nrf2 pathway hyperactivation can assist malignant cells in overcoming oxidative stress, hence increasing cell survival and proliferation