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Slow phase 1 and fast phase 2 If phase 1 is slow then the toxins are mostly staying in the fatty tissue around the body and not starting the process to be activated and then excreted

The only exceptions are the amino acids responsible for the interaction with the SH3 domain from SNX9-SH3 (pLDDT values ~ 80)

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Amyloidogenic proteins then interact with cardiolipin in the outer membrane to induce an apoptotic cascade, resulting in neuronal cell death and, ultimately, neurodegenerative disease