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Low vitamin D and elevated immunoreactivity against Epstein-Barr virus before first clinical manifestation of multiple sclerosis

Additionally, we performed quantitative amino acid profiling of individuals from konzo-prone regions which suggests a deficiency in cystine, the precursor for the antioxidant glutathione, which is required by GPx3 to effectively remove ROS from circulation 22

Because biologic drugs (like adalimumab and infliximab) are large, complex proteins, the patient's immune system can sometimes recognize them as foreign and produce anti-drug antibodies against them