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Eskra JN, Dodge A, Schlicht MJ, Bosland MC

The enzyme carnitine palmitoyltransferase II (CPT II) which is localized in the inner mitochondrial membrane converts acylcarnitines back to acyl CoAs and free L-carnitine, which exits the mitochondria and serves as the substrate for CPT I to form more acylcarnitine [1, 43]

49 PPAR, PGC1, AMPK signaling network Exercise training efficiently induces mitochondria and energy metabolic changes to meet the increased demand of oxygen and energy in the heart

Reactive oxygen/nitrogen species exacerbate the severity of asthma symptoms by activating inflammatory mediators that cause airway smooth muscle contraction, promote mucus hypersecretion, increase the permeability of lung capillaries, and damage cell membranes