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Nrf2 and Oxidative Stress: A General Overview of Mechanisms and Implications in Human Disease 11(12)

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However, current investigations of histone lactylation modifications have predominantly focused on specific modification sites, particularly H3K18 [20, 37, 65], while studies examining modifications at other histone sites remain limited

In this regard, this expert opinion document is expected to increase awareness among physicians about conceptual, clinical, and therapeutic aspects of DPN and to assist them in timely recognition of DPN and translating this information into their clinical practice for best practice in the management of patients with DPN