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(5.8) Adverse Reactions/Side Effects There have been rare reports of the following types of reactions: Allergic anaphylactoid reactions following large intravenous doses of thiamine, urticaria, periorbital and digital edema (6) Dermatologic rash, erythema, pruritus (6) CNS headache, dizziness, agitation, anxiety (6) Ophthalmic diplopia (6) To report SUSPECTED ADVERSE REACTIONS, contact Hospira, Inc