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In addition, we also identified 11 uniquely downregulated genes in Mlkl / -d3-PPE animals as compared to Mlkl AA -d3-PPE and Ripk1 D138N/D138N -d3-PPE animals, which included known AAA and inflammation-associated genes like Ctla4 [21], Marco [22, 23], Csf3 [24], Chil1 [25] and Olfm4 [26, 27] (Fig