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In STAT3-knockdown MCECs (siSTAT3-transfected), GHK-Cu failed to enhance wound healing in scratch assays (Figures 7A,B) and did not upregulate ZO-1/Occludin expression (Figures 7CF)

New England Journal of Medicine (2025) 2

Patients: A total of 1089 insulin-nave adult patients with T2D inadequately controlled on metformin alone (48%) or in combination with sulfonylurea (51%) were randomized to receive once-weekly Ozempic injection 0.5 mg (n=362), once-weekly Ozempic injection 1 mg (n=360), or once-daily insulin glargine U-100 (n=360)