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This study systematically reviews existing evidence regarding the safety and efficacy of asfotase alfa in treating HPP

Estimation of AsA-GSH cycle AsA content The spectrophotometric method reported by Malik and Singh (2005) was adapted for AsA determination, and the AsA level was computed as mg kg 1 (fresh weight basis)

Therefore, chronic inflammation and oxidative stress are not only the core pathological mechanisms of CKD-associated sarcopenia but also promote each other to form a vicious cycle of inflammation-oxidative stress-muscle loss, which exacerbates the deterioration of CKD patients

Discussion In this study, we have shown that rat haploid cells produced under our culture conditions were able to produce healthy and fertile offspring