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Hyaluronidase (HAase)-loaded nanoparticles directly degrade hyaluronic acid, a major ECM component that contributes to elevated interstitial pressure and impaired drug delivery

Extrapulmonary manifestations (Table 1) were observed in a subset of patients, including myocardial damage (6, 2.06%), rash (6, 2.06%), gastrointestinal symptoms such as abdominal bloating, vomiting, and diarrhea (15, 5.15%), and thoracodynia (1, 0.34%)

Ivashkiv LB (2018) IFN: signalling, epigenetics and roles in immunity, metabolism, disease and cancer immunotherapy

Each growth cycle produces thinner, shorter hairs until the follicle eventually stops producing visible hair altogether