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Iracheta-Vellve A, Petrasek J, Gyogyosi B, Bala S, Csak T, Kodys K, et al

The apparent discrepancy between the cytotoxic potencies of the thiol compounds and their respective rates of H 2 O 2 formation in the reconstituted reaction mixture (in the presence of catalytically active SOD1) was reconciled when thiol oxidation was performed in the presence of cystine (oxidized cysteine dimer, CS-SC, 200 M) a component of the standard DMEM cell growth medium used in our cytotoxicity experiments