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Genomic research on pests has helped identify how different resistance profiles are produced and maintained, such as by linkage, epistasis, and structural variation 5,6,7,8 , and can indicate how specific types of resistance become geographically widespread via gene flow between populations 9 or species 10 or by multiple independent substitutions of the same allele 11,12

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However, the recombinant constructs of Gsh2-Gsh1 and Pro1-GshB with a flexible linker have not been exploited for improving intracellular GSH synthesis until now