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A phase 3 study (NCT04822181), which enrolled 1200 patients with biopsy-proven MASH and fibrosis, is currently ongoing to assess the benefit of OW subcutaneous semaglutide 2 mg in this setting 93

Jcker M, Gnther A, Gradl G, Fonatsch C, Krueger G, Diehl V, et al

A cell-culture study, animal model, biochemical assay, or tissue-based experiment may require different controls and endpoints

Cagrilintide, as a long-acting amylin analogue, binds to the same receptors with high affinity and full agonist activity, but remains active in the circulation for a much longer duration