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Description

Hence, to elucidate the molecular mechanisms for free iron accumulation linked to ferroptosis induction in COPD pathogenesis, we focused on NCOA4-mediated ferritinophagy in a CSE-treated bronchial epithelial cell

(trx = treatment

Substantial iron deposition was found in alveolar epithelial cells of lung fibrosis samples, whereas deferoxamine (DFO) prevented lung fibrosis progression and ferroptosis by stabilizing iron metabolism in the lung (136)

Primary nootropic metabolites PUFAs Polyunsaturated acids or PUFAs, especially n-3 and omega 6 (n-6), are essential components of nerve cell membranes that help maintain optimal nerve and brain functions [108]