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In a human pancreatic cancer cell model, the cytoplasmic caudal motif of MUC1 directly binds to the promoter region of multidrug resistance ( MDR ) gene ATP-binding cassette ( ABC-C1 ) gene and upregulates the level of multidrug resistance-associated protein 1 (MRP1) protein encoded by Abcc1 through the Akt-dependent pathway, MRP1-9 is a class of the ABC transporters that have been positively linked to the MDR phenotype in cancer cells

Proper storage is critical

Before reading this article and viewing the video, teachers could provide students with a Vocabulary Preview learning strategy to help engage prior knowledge and introduce new terminology

Besides, the surface protein CD38 can enhance intracellular Ca 2+ levels to promote RasGRP2/Rap1-mediated CLL cell adhesion and migration [76, 77]