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Suzuki M, Shiraha H, Fujikawa T, Takaoka N, Ueda N, Nakanishi Y, et al

High levels of homocysteine are likely to negatively affect the formation of the sulfated amino sugars, because although some sulfates are present in the diet, the sulfoxidation of cysteine is an important source of sulfate molecules

This process cant happen when your immune system blocks your intrinsic factor

Therefore, our study explored the impact of metformin on the proliferation, differentiation, and ferroptosis of endogenous NSCs during SCI repair through in vitro and in vivo experiments, further highlighting the role and molecular mechanisms of metformin in neuroregeneration and neuroprotection