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Perini, P

This imbalance between proteinase and antiproteinase, along with the increased inflammation observed in A1ATD (mediated by LTB4, CXCL8, and TNF), is the primary mechanism leading to lung disease

Orange: Information and Storage Processing

When a score falls significantly above or below the mean, it is referred to as being a distance from the mean, e.g., 1 or 2 standard deviations from the mean