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MAPK pathways, including ERK, p38, and JNK are generally pro-survival, and increased activation of these pathways is generally correlated with increased platinum resistance [35]

This supports that ATP requirements escalate in repair mechanisms due to oxidative damage 17

The smaller peaks for (S-S) and (C-S) were still visible, however a clear trend could not be seen due to the overlap with phosphate bands: E.g ., the (S-N = O) mode could hardly be observed in the difference spectra