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To illustrate the success of the application and the way of application efficacy, it may be instructive to mention the noted effect in the recovery of the transected sciatic nerve injury (providing the efficacy of the once intraperitoneal, intragastric application much like the application into the tube with inserted nerve stumps) (Gjurasin et al., 2010)

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Some patients receiving an intramuscular LAI may at times not be cooperative or compliant

A supplementation with methylfolate alone is not always effective, as it has to interact closely with vitamin B12