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Bertoldo et al, 2020a

Genetic variation in glutathione synthesis genes (GCLC, GCLM) and detoxification pathways (GST polymorphisms) influences baseline glutathione levels and responsiveness to supplementation

Increasing evidence of astrocyte dysfunction in disease pathology has spurred interest in developing astrocyte-targeted therapeutic strategies (Figure 1, Table 2

At the same time, it preserved the homeostasis of CD8+ splenocytes, maintaining their cytotoxic function without provoking an excessive inflammatory response [50], suggesting Epitalons role in recalibrating, rather than overactivating, immune function