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Description

4D) via the expression of glucose transporter 1 and glutaminase, respectively

We previously developed chemoproteomic strategies to systematically map itaconate modifications, identifying thousands of itaconated proteins in macrophages 14,18

Meanwhile, ROT administration significantly decreased the GSH level in the hippocampus ( P =2.3 10 -3 ) compared to NC, whereas in the MH+ROT group, the GSH level ( P =3.8 10 -2 ) was elevated to 152.27, rather higher than the 100.77 in the ROT groups (Fig