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The GPOX activity of VA13 was increased by 9% and 23% at MDS and SDS conditions, whereas GPOX activity of VA15 was increased by 18% and 29% at MDS and SDS conditions, respectively in comparison with control treatment

These enzymes function in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione

Chromosome 8 contains some highly promising candidate genes to pursue using functional genetics approaches such as knock-out mutations using Hg accumulation to quantify the effects of mutants

2018;28:776-786 e775