glutathione s transferase and oxidative stress S-transferase Frontiers | Signaling pathways of

27-hydroxycholesterol induces aberrant morphology and synaptic dysfunction in hippocampal neurons

At the end of the fed-batch cultures, the percentage of HCPs associated with the extracellular region, extracellular matrix, and extracellular space was significantly lower due to the emergence of HCPs associated with the cytoplasm, melanosome, and ER

Furthermore, when NADPH concentration was increased, anti-BPDE was formed by the action of CYP1A1/1B1, whereas under conditions of higher NAD concentration, The system with a relatively higher concentration of NADPH favored the formation of anti-BPDE via P450 1A1/P450 1B1, AKR1A1 mediated formation of BP-7,8-dione was favored

Statistical analysis Results represent the mean of three independent experiments, each performed in triplicate, with error bars showing the S.E.M