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Vinet et al

The liver needs NADPH to neutralize toxins (and hormones) using the cytochrome P450 pathways

Supplementation trials show dose-dependent benefits for type II diabetics

5 Using elevated metabolite levels (ie, serum methylmalonic acid [MMA] or homocysteine [Hcy]) to define deficiency, the screening serum B 12 cutoff used in many diagnostic algorithms has been raised to 250 pg/mL to 300 pg/mL to provide greater sensitivity