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Sorbitol treatment extends lifespan and induces the osmotic stress response in Caenorhabditis elegans

Treatment for B12 deficiency without neurological involvement: For patients with haematological manifestations only (macrocytic anaemia) or asymptomatic deficiency, the regimen is hydroxocobalamin 1mg intramuscularly three times weekly for two weeks (total of six injections), followed by maintenance of 1mg every three months for life

They work by mimicking the hormone glucagon-like-peptide-1 (GLP-1)