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These levels peak and stabilize, maintaining a plateau during much of adulthood

Selby et al

Psychiatry 42 , 349358 (1997)

In human ALS motor cortex, microglia show increased expression of Iba1 and CD68 (i.e., macrophages and monocytes marker), with CD68 levels strongly correlating with TDP-43 pathology (Swanson et al., 2023)