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Keep it away from the back wall of the refrigerator where temperatures can drop below freezing

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The diminished reserves act as a red flag, signaling a potential imbalance that extends beyond the livers immediate struggles

Notably, although gcs-1 induction is impaired in CSN-deficient animals (Figures 3A,B, 2B upper panel), the high basal gcs-1 expression and increased expression of other phase 2 detoxification genes, e.g., gst-7 (Figure 2B lower panel, see Additional file 2: Figure S5), is sufficient to confer increased oxidative stress resistance (Figures 2C and 3C) [17]